How to Use moDiNA

Figure 1: Overview of the moDiNA pipeline. Created with BioRender.com.

We developed a Python package that enables the execution of individually specified configurations, allowing flexible and reproducible analyses tailored to specific research needs.

For a more comprehensive and systematic evaluation of different configurations, we implemented a Nextflow pipeline. This pipeline is designed to facilitate the execution of multiple configurations across various simulation scenarios, enabling users to assess the performance of different settings and identify optimal configurations for their specific research questions. Additionally, we provide evaluation scripts to analyze the results generated by the Nextflow pipeline, allowing users to evaluate the performance of different configurations and make informed decisions about their analysis strategies.

Please have a look at the respective sections for detailed instructions on how to use the Python package and the Nextflow pipeline. For a more detailed overview of the individual steps, please refer to Differential Network Analysis.